Epi-Cryptoacetalide

Modify Date: 2024-01-24 17:35:20

Epi-Cryptoacetalide Structure
Epi-Cryptoacetalide structure
Common Name Epi-Cryptoacetalide
CAS Number 132152-57-9 Molecular Weight 286.366
Density 1.2±0.1 g/cm3 Boiling Point 464.9±45.0 °C at 760 mmHg
Molecular Formula C18H22O3 Melting Point N/A
MSDS N/A Flash Point 199.8±23.3 °C

 Use of Epi-Cryptoacetalide


Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with Ki values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities[1].

 Names

Name Epi-Cryptoacetalide
Synonym More Synonyms

 Epi-Cryptoacetalide Biological Activity

Description Epi-cryptoacetalide is a natural diterpenoid. Epi-cryptoacetalide reveals high affinity to ER-α and PGE2 receptor (EP2 subtype) with Ki values of 0.3 μM and 1.92 μM, respectively. Epi-cryptoacetalide has anti-endometriosis activities[1].
Related Catalog
Target

Ki: 0.3 μM (ER-α) and 1.92 μM (EP2 subtype)[1]

In Vitro Epi-cryptoacetalide 是丹参中的一种成分,具有散瘀止痛、活血通经、除烦等功效; 月经不调,经闭,痛经,脘腹作痛,胸腹刺痛,热痹,疮疡疮毒,失眠,肝脾肿痛,心绞痛。
References

[1]. Herbert Situmorang, et al. IN-SILICO dynamic analysis of Sulawesi propolis as anti-endometriosis drug: Interaction study with TNF alpha receptor, NF-kB, estrogen receptor, progesterone receptor and prostaglandin receptor. Ann Med Surg (Lond). 2021 Jun 17;67:102459.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 464.9±45.0 °C at 760 mmHg
Molecular Formula C18H22O3
Molecular Weight 286.366
Flash Point 199.8±23.3 °C
Exact Mass 286.156891
LogP 4.39
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.580

 Synonyms

Spiro[furan-2(3H),3'(1'H)-naphtho[1,2-c]furan]-1'-one, 4,5,6',7',8',9'-hexahydro-4,6',6'-trimethyl-, (2R,4R)-
(2R,4R)-4,6',6'-Trimethyl-4,5,6',7',8',9'-hexahydro-1'H,3H-spiro[furan-2,3'-naphtho[1,2-c]furan]-1'-one