NSC 624206
NSC 624206 structure
|
Common Name | NSC 624206 | ||
|---|---|---|---|---|
| CAS Number | 13116-77-3 | Molecular Weight | 410.508 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H33Cl2NS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC 624206NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: ~9 μM (ubiquitin E1)[1] |
| In Vitro | NSC624206 prevents in vitro ubiquitination of the cell cycle regulator p27 as well as inducing an accumulation of p27 in the HepG2 liver cancer cell line[1]. NSC624206 clearly reduces ubiquitin-E1 thioesters in a concentration-dependent manner with an IC50 of 13 μM[1]. NSC624206 (10 nM-10 μM; 24 hours) induces accumulation of p27 in cells[1]. Western Blot Analysis[1] Cell Line: Kip16 cells Concentration: 10 nM-10 μM Incubation Time: 24 hours Result: Induced accumulation of p27. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C19H33Cl2NS2 |
|---|---|
| Molecular Weight | 410.508 |
| Exact Mass | 409.143158 |
| InChIKey | JQHUAYXPNPTQRO-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCNCCSSCc1ccc(Cl)cc1.Cl |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Decylamine, N-(2-((p-chlorobenzyl)dithio)ethyl)-, hydrochloride |
| MFCD01736096 |
| 1-Decanamine, N-[2-[[(4-chlorophenyl)methyl]dithio]ethyl]-, hydrochloride (1:1) |
| N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride |
| N-(2-((4-Chlorobenzyl)dithio)ethyl)-1-decanamine hydrochloride |
| N-{2-[(4-Chlorobenzyl)disulfanyl]ethyl}-1-decanamine hydrochloride (1:1) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What English synonyms does N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride have? |
| A: English synonyms of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride: Decylamine, N-(2-((p-chlorobenzyl)dithio)ethyl)-, hydrochloride, MFCD01736096, 1-Decanamine, N-[2-[[(4-chlorophenyl)methyl]dithio]ethyl]-, hydrochloride (1:1), N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride, N-(2-((4-Chlorobenzyl)dithio)ethyl)-1-decanamine hydrochloride, N-{2-[(4-Chlorobenzyl)disulfanyl]ethyl}-1-decanamine hydrochloride (1:1). |
| Q: What is the molecular formula of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: Molecular formula of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is C19H33Cl2NS2. |
| Q: What is the molecular weight of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: Molecular weight of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is 410.508. |
| Q: What is the Chinese name of 13116-77-3? |
| A: Chinese name of 13116-77-3 is NSC624206. |
| Q: What is the CAS number of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: CAS number of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is 13116-77-3. |
| Q: What is the English name of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: The English name of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride. |
| Q: What is the SMILES notation of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: SMILES notation of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is CCCCCCCCCCNCCSSCc1ccc(Cl)cc1.Cl. |
| Q: What is the InChIKey of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: InChIKey of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride is JQHUAYXPNPTQRO-UHFFFAOYSA-N. |
| Q: What are the uses of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride? |
| A: Main uses of N-(2-((p-Chlorobenzyl)dithio)ethyl)decylamine hydrochloride: NSC624206 is an inhibitor of ubiquitin E1 (UBA1), with an IC50 of ~9 μM. NSC624206 specifically blocks ubiquitin-thioester formation (IC50=13 μM) but has no effect on ubiquitin adenylation[1]. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |