1-isothiocyanato-PEG3-Azide

Modify Date: 2025-08-25 18:51:28

1-isothiocyanato-PEG3-Azide Structure
1-isothiocyanato-PEG3-Azide structure
 Common Name 1-isothiocyanato-PEG3-Azide
CAS Number 1310686-23-7 Molecular Weight 260.31
Density N/A Boiling Point N/A
Molecular Formula C9H16N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-isothiocyanato-PEG3-Azide


1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Isothiocyanato-PEG3-azide

 1-isothiocyanato-PEG3-Azide Biological Activity

Description 1-Isothiocyanato-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H16N4O3S
Molecular Weight 260.31
InChIKey WGVGUDRBZOFJRC-UHFFFAOYSA-N
SMILES [N-]=[N+]=NCCOCCOCCOCCN=C=S
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