Thiol-C9-PEG4 structure
|
Common Name | Thiol-C9-PEG4 | ||
|---|---|---|---|---|
| CAS Number | 130727-41-2 | Molecular Weight | 336.53000 | |
| Density | 0.995 g/mL at 25ºC | Boiling Point | 446.5ºC at 760 mmHg | |
| Molecular Formula | C17H36O4S | Melting Point | N/A | |
| MSDS | USA | Flash Point | >110ºC | |
Use of Thiol-C9-PEG4Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 0.995 g/mL at 25ºC |
|---|---|
| Boiling Point | 446.5ºC at 760 mmHg |
| Molecular Formula | C17H36O4S |
| Molecular Weight | 336.53000 |
| Flash Point | >110ºC |
| Exact Mass | 336.23300 |
| PSA | 86.72000 |
| LogP | 3.46920 |
| Vapour Pressure | 7.55E-10mmHg at 25°C |
| Index of Refraction | n 20/D 1.476 |
| Storage condition | Refrigerator, Under Inert Atmosphere |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| RIDADR | UN 3334 |
| HS Code | 2930909090 |
|
~55%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Canaria, Christie A.; Smith, Jeffrey O.; Yu; Fraser, Scott E.; Lansford, Rusty Tetrahedron Letters, 2005 , vol. 46, # 28 p. 4813 - 4816 |
|
~%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Monatshefte fur Chemie, , vol. 138, # 3 p. 245 - 252 |
|
~70%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Hahn, Christoph D.; Tinazli, Ali; Hoelzl, Martin; Leitner, Christa; Frederix, Filip; Lackner, Bernd; Mueller, Norbert; Klampfl, Christian; Tampe, Robert; Gruber, Hermann J. Monatshefte fur Chemie, 2007 , vol. 138, # 3 p. 245 - 252 |
|
~%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Journal of the American Chemical Society, , vol. 113, # 1 p. 12 - 20 |
|
~%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Journal of the American Chemical Society, , vol. 113, # 1 p. 12 - 20 |
|
~%
Thiol-C9-PEG4 CAS#:130727-41-2 |
| Literature: Monatshefte fur Chemie, , vol. 138, # 3 p. 245 - 252 |
| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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