Thiol-C9-PEG4

Modify Date: 2025-08-26 10:04:42

Thiol-C9-PEG4 Structure
Thiol-C9-PEG4 structure
Common Name Thiol-C9-PEG4
CAS Number 130727-41-2 Molecular Weight 336.53000
Density 0.995 g/mL at 25ºC Boiling Point 446.5ºC at 760 mmHg
Molecular Formula C17H36O4S Melting Point N/A
MSDS USA Flash Point >110ºC

 Use of Thiol-C9-PEG4


Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-(11-sulfanylundecoxy)ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Thiol-C9-PEG4 Biological Activity

Description Thiol-C9-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 0.995 g/mL at 25ºC
Boiling Point 446.5ºC at 760 mmHg
Molecular Formula C17H36O4S
Molecular Weight 336.53000
Flash Point >110ºC
Exact Mass 336.23300
PSA 86.72000
LogP 3.46920
Vapour Pressure 7.55E-10mmHg at 25°C
Index of Refraction n 20/D 1.476
Storage condition Refrigerator, Under Inert Atmosphere

 Safety Information

Personal Protective Equipment Eyeshields;Gloves
RIDADR UN 3334
HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

Triethylene glycol mono-11-mercaptoundecyl ether
20-sulfanyl-3,6,9-trioxa-1-icosanol
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