FR 122047 hydrochloride
Modify Date: 2025-12-01 20:00:57
FR 122047 hydrochloride structure
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Common Name | FR 122047 hydrochloride | ||
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| CAS Number | 130717-51-0 | Molecular Weight | 459.98900 | |
| Density | N/A | Boiling Point | 562.7ºC at 760 mmHg | |
| Molecular Formula | C23H26ClN3O3S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 294.1ºC | |
Use of FR 122047 hydrochlorideFR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo[1][2][3]. |
| Name | FR 122047 hydrochloride,1-[[4,5-bis(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazinehydrochloride |
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| Description | FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo[1][2][3]. |
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| Related Catalog | |
| Target |
COX-1:28 nM (IC50) |
| References |
| Boiling Point | 562.7ºC at 760 mmHg |
|---|---|
| Molecular Formula | C23H26ClN3O3S |
| Molecular Weight | 459.98900 |
| Flash Point | 294.1ºC |
| Exact Mass | 459.13800 |
| PSA | 83.14000 |
| LogP | 4.55970 |
| Vapour Pressure | 1.1E-12mmHg at 25°C |
| InChIKey | YWMAVHIKOAOSFM-UHFFFAOYSA-N |
| SMILES | COc1ccc(-c2nc(C(=O)N3CCN(C)CC3)sc2-c2ccc(OC)cc2)cc1.Cl |