L-Isoleucine-d1

Modify Date: 2024-01-10 17:28:00

L-Isoleucine-d1 Structure
L-Isoleucine-d1 structure
Common Name L-Isoleucine-d1
CAS Number 127290-60-2 Molecular Weight 132.18
Density N/A Boiling Point N/A
Molecular Formula C6H12DNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Isoleucine-d1


L-Isoleucine-d1 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.

 Names

Name (2S,3Ξ)-2-amino-2-deuterio-3-methyl-pentanoic acid
Synonym More Synonyms

 L-Isoleucine-d1 Biological Activity

Description L-Isoleucine-d1 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Arkhipov SG, et al. New hydrophobic L-amino acid salts: maleates of L-leucine, L-isoleucine and L-norvaline. Acta Crystallogr C Struct Chem. 2015 Jul;71(Pt 7):584-92.

 Chemical & Physical Properties

Molecular Formula C6H12DNO2
Molecular Weight 132.18
Exact Mass 132.10100
PSA 63.32000
LogP 1.14470

 Synonyms

L-ISOLEUCINE-2-D1
α-Deutero-isoleucin
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