4-Hydroxybenzenesulfonic acid

CAS#127-82-2 [anhydrous CAS
no.]
Manufacturer
Commercial Name(s)
Zinc phenolsulfonate

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Section 3. Hazards Identification
Potential Acute Health Effects Hazardous in case of eye contact (irritant). Slightly hazardous in case of skin contact (irritant), of ingestion, of
inhalation.
Potential Chronic HealthCARCINOGENIC EFFECTS: Not available.
EffectsMUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.

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Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Cold water may be used.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

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Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
These products are carbon oxides (CO, CO2), sulfur oxides (SO2, SO3...). Some metallic oxides.
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available.
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onWhen heated to decomposition it emits irritating and toxic fumes of sulfur oxides and zinc.
Fire Hazards
Special Remarks on Explosion Not available.
Hazards
Zinc phenolsulfonate

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Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.

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Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe dust. Avoid contact with eyes. Wear suitable protective clothing. If ingested, seek
medical advice immediately and show the container or the label.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Air Sensitive Sensitive to light.
Store in light-resistant containers.

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Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal ProtectionSplash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

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Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Crystalline solid.)OdorOdorless.
Astringent Metallic
Taste
Molecular Weight555.86 g/mole
White.
Color
pH (1% soln/water)Not available.
Boiling PointDecomposes.
Melting PointNot available.
Critical TemperatureNot available.
Specific Gravity>1 (Water = 1)
Not applicable.
Vapor Pressure
Vapor DensityNot available.
Not available.
Volatility
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water.
SolubilityEasily soluble in cold water, hot water.
Zinc phenolsulfonate

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Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Excess heat, incompatible materials, dust generation
Conditions of Instability
Not available.
Incompatibility with various
substances
CorrosivityNon-corrosive in presence of glass.
Special Remarks onEffloresces in dry air.
ReactivityLoses all water at about 120 deg. C.
Air and light sensitive. Turns pink on extended exposure to light and air.
Incompatible with alkali soaps and ferric salts. Ferric salts turn material red or violet.
Not available.
Special Remarks on
Corrosivity
PolymerizationWill not occur.

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Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsAcute oral toxicity (LD50): 1800 mg/kg [Rat].
Chronic Effects on Humans Not available.
Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Special Remarks onLethal Dose/Conc:
Toxicity to AnimalsLC [Rat] - Route: Inhalation; Dose: >208 gm/m3/1H
LD[Guinea Pig] - Route: Skin; Dose: >3000 mg/kg
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherAcute Potentia Health Effects:
Toxic Effects on HumansSkin: May cause skin irritation.
Eyes: Can cause moderate eye irritation with possible pain. May cause corneal damage
Inhalation: Inhalation of dust may cause nose, throat, respiratory tract irritation. Symptoms may include
coughing, sneezing, wheezing.
Ingestion: May be harmful if swallowed. Ingestion of large amounts may cause nausea, vomiting, diarrhea, and
astringent actions (contacting blood vessels or shrinking mucous membranes.

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Section 12. Ecological Information
EcotoxicityNot available.
Not available.
BOD5 and COD
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the ProductsThe products of degradation are less toxic than the product itself.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation
Zinc phenolsulfonate

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Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

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Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
For Zinc Phenolsulfonate (anhydrous CAS no. 127-82-2):
Federal and State
Connecticut hazardous material survey.: Zinc phenolsulfonate
Regulations
Illinois chemical safety act: Zinc phenolsulfonate
New York release reporting list: Zinc phenolsulfonate
Pennsylvania RTK: Zinc phenolsulfonate
Massachusetts RTK: Zinc phenolsulfonate
Massachusetts spill list: Zinc phenolsulfonate
New Jersey: Zinc phenolsulfonate
New Jersey spill list: Zinc phenolsulfonate
Louisiana RTK reporting list: Zinc phenolsulfonate
California Director's List of Hazardous Substances: Zinc phenolsulfonate
SARA 313 toxic chemical notification and release reporting: Zinc phenolsulfonate (listed as Zinc compounds)
CERCLA: Hazardous substances.: Zinc phenolsulfonate: 5000 lbs. (2268 kg)
Zinc Phenolsulfonate, octahydrate is exempt from TSCA Inventory 8(b) listing. However, the anhydrous form
(CAS no. 127-82-2) is on the TSCA 8(b) inventory.
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found
to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsFor Zinc Phenolsulfonate (anhydrous CAS no. 127-82-2):
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No.
204-867-8).
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Listed on National Inventory.
Japan: Listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Not listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC)R22- Harmful if swallowed.S26- In case of contact with eyes, rinse
R36- Irritating to eyes.immediately with plenty of water and seek
medical advice.
S46- If swallowed, seek medical advice
immediately and show this container or label.
Zinc phenolsulfonate
Health Hazard
HMIS (U.S.A.)2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Splash goggles.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

MOLECULAR WEIGHT :

411.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

LC - Lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>208 gm/m3/1H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

225 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

172 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

LD - Lethal dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

>3 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

20 mg/m3/4H/13W-I

TOXIC EFFECTS :

Brain and Coverings - changes in brain weight Liver - changes in liver weight Related to Chronic Data - changes in testicular weight

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

45 mg/m3/3H/13W-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in bladder weight

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),373,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80584 No. of Facilities: 299 (estimated) No. of Industries: 4 No. of Occupations: 12 No. of Employees: 7057 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80584 No. of Facilities: 502 (estimated) No. of Industries: 4 No. of Occupations: 12 No. of Employees: 20492 (estimated) No. of Female Employees: 16580 (estimated)