Mal-PEG4-propargyl

Modify Date: 2025-08-31 16:01:09

Mal-PEG4-propargyl structure	Common Name	Mal-PEG4-propargyl
	CAS Number	1262681-30-0	Molecular Weight	311.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₂₁NO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mal-PEG4-propargyl

Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG4-propargyl

Description	Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₅H₂₁NO₆
Molecular Weight	311.33

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