JTZ-951 hydrochloride
Modify Date: 2024-04-08 18:04:34
JTZ-951 hydrochloride structure
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Common Name | JTZ-951 hydrochloride | ||
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| CAS Number | 1262131-60-1 | Molecular Weight | 376.797 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H17ClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JTZ-951 hydrochlorideA novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2; increases EPO release from Hep3B cells with EC50 of 5.7 uM, increases hemoglobin levels in rats. Anemia Phase 2 Clinical |
| Name | JTZ-951 hydrochloride |
|---|
| Description | A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2; increases EPO release from Hep3B cells with EC50 of 5.7 uM, increases hemoglobin levels in rats. Anemia Phase 2 Clinical |
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| References | References 1. Yosuke Ogoshi, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1320-1325. View Related Products by Target HIF/HIF Prolyl-hydroxylase Anemia |
| Molecular Formula | C17H17ClN4O4 |
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| Molecular Weight | 376.797 |