coumarin-SAHA

Modify Date: 2024-01-02 05:46:03

coumarin-SAHA Structure
coumarin-SAHA structure
Common Name coumarin-SAHA
CAS Number 1260635-77-5 Molecular Weight 346.378
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H22N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of coumarin-SAHA


Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].

 Names

Name N'-hydroxy-N-(4-methyl-2-oxochromen-7-yl)octanediamide
Synonym More Synonyms

 coumarin-SAHA Biological Activity

Description Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].
Related Catalog
References

[1]. Raushan K Singh, et al. Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors. Anal Biochem

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C18H22N2O5
Molecular Weight 346.378
Exact Mass 346.152863
PSA 108.64000
LogP 1.41
Index of Refraction 1.593
Storage condition -20°C

 Synonyms

N-Hydroxy-N'-(4-methyl-2-oxo-2H-chromen-7-yl)octanediamide
Octanediamide, N-hydroxy-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
Coumarin Suberoylanilide Hydroxamic Acid
Coumarin-SAHA