L-156,602

Modify Date: 2024-01-29 13:15:14

L-156,602 structure	Common Name	L-156,602
	CAS Number	125228-51-5	Molecular Weight	840.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₆₄N₈O₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of L-156,602

L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH)[1][2].

Name	l-156,602

Description	L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH)[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Complement System Research Areas >> Inflammation/Immunology
Target	C5a receptor[1][2]
References	[1]. Tsuji RF, et al. Effects of L-156,602, a C5a receptor antagonist, on mouse experimental models of inflammation. Biosci Biotechnol Biochem. 1992 Dec;56(12):2034-6. [2]. Tsuji RF, et al. Anti-inflammatory effects and specificity of L-156,602: comparison of effects on concanavalin A and zymosan-induced footpad edema, and contact sensitivity response. Immunopharmacology. 1995 Feb;29(1):79-87.

Molecular Formula	C₃₈H₆₄N₈O₁₃
Molecular Weight	840.96
Exact Mass	840.45900
PSA	279.95000
LogP	0.19240

L-156,602

Use of L-156,602

Names

L-156,602 Biological Activity

Chemical & Physical Properties