Ambroxol-d5
Ambroxol-d5 structure
|
Common Name | Ambroxol-d5 | ||
|---|---|---|---|---|
| CAS Number | 1246818-80-3 | Molecular Weight | 383.1385 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13D5Br2N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ambroxol-d5Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous particles in the same cells. Ambroxol increases phenol red secretion, a marker of expectorant activity, in mice when administered at doses of 30, 60, or 120 mg/kg. Formulations containing ambroxol have been used in the treatment of acute or chronic respiratory conditions. |
| Name | Ambroxol-d5 |
|---|
| Description | Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous particles in the same cells. Ambroxol increases phenol red secretion, a marker of expectorant activity, in mice when administered at doses of 30, 60, or 120 mg/kg. Formulations containing ambroxol have been used in the treatment of acute or chronic respiratory conditions. |
|---|
| Molecular Formula | C13H13D5Br2N2O |
|---|---|
| Molecular Weight | 383.1385 |
| InChIKey | JBDGDEWWOUBZPM-SCGGTJNOSA-N |
| SMILES | Nc1c(Br)cc(Br)cc1CNC1CCC(O)CC1 |