Alirocumab

Modify Date: 2025-08-25 08:29:31

Alirocumab Structure
Alirocumab structure
Common Name Alirocumab
CAS Number 1245916-14-6 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C6472H9996N1736O2032S42 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Alirocumab


Alirocumab (REGN 727) is a human monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9). Alirocumab specifically binds PCSK9, a down regulator of liver low-density lipoprotein (LDL)-receptors, thereby increasing the ability of the liver to bind LDL-cholesterol (LDL-C) and reducing levels of LDL-C in blood. Alirocumab can be used for the research of hypercholesterolemia[1].

 Names

Name Alirocumab
Synonym More Synonyms

 Alirocumab Biological Activity

Description Alirocumab (REGN 727) is a human monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9). Alirocumab specifically binds PCSK9, a down regulator of liver low-density lipoprotein (LDL)-receptors, thereby increasing the ability of the liver to bind LDL-cholesterol (LDL-C) and reducing levels of LDL-C in blood. Alirocumab can be used for the research of hypercholesterolemia[1].
Related Catalog
References

[1]. Markham A. Alirocumab: First Global Approval. Drugs. 2015;75(14):1699-1705.

 Chemical & Physical Properties

Molecular Formula C6472H9996N1736O2032S42
InChIKey CATWCRUATKKAAQ-UHFFFAOYSA-N
SMILES O=P(O)(O)OCC(O)CO.[Na].[Na]

 Synonyms

ALIROCUMAB
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