SGL5213

Modify Date: 2025-08-29 12:37:14

SGL5213 Structure
SGL5213 structure
Common Name SGL5213
CAS Number 1240305-17-2 Molecular Weight 669.85
Density N/A Boiling Point N/A
Molecular Formula C37H55N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SGL5213


SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].

 Names

Name SGL5213

 SGL5213 Biological Activity

Description SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].
Related Catalog
Target

IC50: 29nM/20 nM (hSGLT1/ hSGLT2)[1].

References

[1]. Kuroda S, et al. Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment. Bioorg Med Chem. 2019 Jan 15;27(2):394-409.

 Chemical & Physical Properties

Molecular Formula C37H55N3O8
Molecular Weight 669.85
InChIKey MUBBPBZRFJGZEU-XSPPBVGUSA-N
SMILES COc1cc(C(C)C)c(Cc2ccc(C=CC(C)(C)C(=O)NC(C)(C)C(=O)NCCN(C)C)cc2)cc1C1OC(CO)C(O)C(O)C1O
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