AZD2423

Modify Date: 2024-01-10 17:27:33

AZD2423 structure	Common Name	AZD2423
	CAS Number	1229603-37-5	Molecular Weight	425.93
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₉ClFN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AZD2423

AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC50 of 1.2 nM for CCR2 Ca2+ flux [1][2][3].

Name	AZD2423

Description	AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC50 of 1.2 nM for CCR2 Ca2+ flux [1][2][3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Immunology/Inflammation >> CCR Research Areas >> Neurological Disease
Target	CCR2
In Vitro	AZD2423 inhibits MCP-1 induced calcium mobilization and chemotaxis of THP-1 cell line with an IC50 of 4 nM[1].
References	[1]. AZD2423. [2]. John G. Cumming. CCR2 antagonists for the treatment of neuropathic pain: The discovery and development of AZD2423. [3]. Kalliomäki J, et al. A randomized, double-blind, placebo-controlled trial of a chemokine receptor 2 (CCR2) antagonist in posttraumatic neuralgia. Pain. 2013 May;154(5):761-7.

Molecular Formula	C₂₀H₂₉ClFN₅O₂
Molecular Weight	425.93

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AZD2423
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: AZD2423
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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AZD2423

Use of AZD2423

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AZD2423 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.