TPN171

Modify Date: 2024-01-02 18:52:57

TPN171 structure	Common Name	TPN171
	CAS Number	1229018-87-4	Molecular Weight	441.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₅N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TPN171

TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH)[1].

Name	TPN171

Description	TPN171 is a potent, selective and oral bioavailable inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 of 0.62 nM, being developed for the treatment of pulmonary arterial hypertension (PAH)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Target	PDE5:0.62 nM (IC50)
References	[1]. Wang Z, et al. Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. J Med Chem. 2019 May 23;62(10):4979-4990.

Molecular Formula	C₂₄H₃₅N₅O₃
Molecular Weight	441.57

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TPN171
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TPN171
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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TPN171

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.