Granisetron-d3

Modify Date: 2024-01-14 19:16:43

Granisetron-d3 Structure
Granisetron-d3 structure
Common Name Granisetron-d3
CAS Number 1224925-76-1 Molecular Weight 315.43
Density N/A Boiling Point N/A
Molecular Formula C18H21D3N4O Melting Point 290-292°C
MSDS N/A Flash Point N/A

 Names

Name GRANISETRON-D3

 Granisetron-d3 Biological Activity

Description Granisetron-d3 (1-methyl-d3) 是 Granisetron氘代物[1]。
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Melting Point 290-292°C
Molecular Formula C18H21D3N4O
Molecular Weight 315.43
Storage condition -20°C Freezer