(R)-Larotrectinib

Modify Date: 2025-08-25 11:53:18

(R)-Larotrectinib Structure
(R)-Larotrectinib structure
 Common Name (R)-Larotrectinib
CAS Number 1223404-68-9 Molecular Weight 428.44
Density N/A Boiling Point N/A
Molecular Formula C21H22F2N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Larotrectinib


(R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases[1]

 Names

Name (R)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

 (R)-Larotrectinib Biological Activity

Description (R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases[1]
Related Catalog
Target

TrkA:28.5 nM (IC50)

References

[1]. Julia Haas, et al. SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS. WO2010048314A1 (compound 93)

 Chemical & Physical Properties

Molecular Formula C21H22F2N6O2
Molecular Weight 428.44
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Chemsrc provides (R)-Larotrectinib(CAS#:1223404-68-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (R)-Larotrectinib are included as well.>> amp version: (R)-Larotrectinib

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