N-Acetylglycine-d5

Modify Date: 2024-02-03 12:20:44

N-Acetylglycine-d5 Structure
N-Acetylglycine-d5 structure
Common Name N-Acetylglycine-d5
CAS Number 1219805-82-9 Molecular Weight 122.13
Density N/A Boiling Point N/A
Molecular Formula C4H2D5NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-Acetylglycine-d5


N-Acetylglycine-d5 is the deuterium labeled N-Acetylglycine. N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.

 Names

Name N-Acetyl-d3-glycine-2,2-d2

 N-Acetylglycine-d5 Biological Activity

Description N-Acetylglycine-d5 is the deuterium labeled N-Acetylglycine. N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Harper MS, et al. Toxicology studies with N-acetylglycine. Food Chem Toxicol. 2010 May;48(5):1321-7.

 Chemical & Physical Properties

Molecular Formula C4H2D5NO3
Molecular Weight 122.13
Exact Mass 122.07400
PSA 66.40000
Storage condition 2-8°C