Ketopioglitazone-d4

Modify Date: 2024-02-06 14:17:06

Ketopioglitazone-d4 Structure
Ketopioglitazone-d4 structure
Common Name Ketopioglitazone-d4
CAS Number 1215370-26-5 Molecular Weight 374.45
Density N/A Boiling Point N/A
Molecular Formula C19H14D4N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ketopioglitazone-d4


Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.

 Names

Name 5-[[4-[2-(5-acetylpyridin-2-yl)ethoxy]-2,3,5,6-tetradeuteriophenyl]methyl]-1,3-thiazolidine-2,4-dione
Synonym More Synonyms

 Ketopioglitazone-d4 Biological Activity

Description Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C19H14D4N2O4S
Molecular Weight 374.45
Exact Mass 374.12400
PSA 114.15000
LogP 3.07570

 Synonyms

Keto Pioglitazone-d4 (M-III)
Keto-Pioglitazone-Labeled d4
[2H4]-Pioglitazone ketone