TCV-309 chloride
Modify Date: 2025-09-26 15:50:47
TCV-309 chloride structure
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Common Name | TCV-309 chloride | ||
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| CAS Number | 121494-09-5 | Molecular Weight | 629.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H34BrClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TCV-309 chlorideTCV-309 chloride is a platelet activating factor (PAF) antagonist. (1) TCV-309 chloride specifically inhibited PAF-induced aggregation of rabbit and human platelets. (2) TCV-309 chloride selectively inhibited the PAF-induced hypotension, hemoconcentration and death with ED50 values of 2.7, 6.4 and 1.7 micrograms/kg (i.v.), respectively. TCV-309 (chloride) most potently protected mice from death induced by PAF and due to anaphylactic shock with ED50 values of 2.1 and 2.6 micrograms/kg (i.v.), respectively. (3) TCV-309 chloride also reversed PAF-induced hypotension and endotoxin-induced hypotension in rats with ED50 values of 3.3 and 1.2 micrograms/kg (i.v.), respectively. |
| Name | TCV-309 chloride |
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| Synonym | More Synonyms |
| Description | TCV-309 chloride is a platelet activating factor (PAF) antagonist. (1) TCV-309 chloride specifically inhibited PAF-induced aggregation of rabbit and human platelets. (2) TCV-309 chloride selectively inhibited the PAF-induced hypotension, hemoconcentration and death with ED50 values of 2.7, 6.4 and 1.7 micrograms/kg (i.v.), respectively. TCV-309 (chloride) most potently protected mice from death induced by PAF and due to anaphylactic shock with ED50 values of 2.1 and 2.6 micrograms/kg (i.v.), respectively. (3) TCV-309 chloride also reversed PAF-induced hypotension and endotoxin-induced hypotension in rats with ED50 values of 3.3 and 1.2 micrograms/kg (i.v.), respectively. |
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| Related Catalog | |
| References |
| Molecular Formula | C30H34BrClN4O4 |
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| Molecular Weight | 629.97 |
| Storage condition | 2-8℃ |
| TCV-309 (chloride) |