CAY10621(SKI 5C)
Modify Date: 2024-01-02 11:30:57
CAY10621(SKI 5C) structure
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Common Name | CAY10621(SKI 5C) | ||
|---|---|---|---|---|
| CAS Number | 120005-55-2 | Molecular Weight | 435.640 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 519.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C26H45NO4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 267.7±32.9 °C | |
Use of CAY10621(SKI 5C)CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research[1]. |
| Name | (S)-tert-butyl 4-(hexadec-2-ynoyl)-2,2-dimethyloxazolidine-3-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research[1]. |
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| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 519.0±60.0 °C at 760 mmHg |
| Molecular Formula | C26H45NO4 |
| Molecular Weight | 435.640 |
| Flash Point | 267.7±32.9 °C |
| Exact Mass | 435.334869 |
| PSA | 55.84000 |
| LogP | 8.67 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.478 |
| RIDADR | NONH for all modes of transport |
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![4,8-dicyano-1,2,4,8-tetramethyl-3,9-dioxatricyclo-[5.2.1.02,6]decane structure](https://www.chemsrc.com/caspic/203/785828-30-0.png)
| Precursor 9 | |
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| DownStream 1 | |
CAS#:123-78-4|
Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma.
Liver Int. 32(2) , 331-8, (2012) Sphingosine kinase 1 (SphK1), which phosphorylates sphingosine to sphingosine-1-phosphate (S1P), is overexpressed in various types of cancers, and may act as an oncogene in tumorigenesis. However, lit... |
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