9,10-dihydroxystearic acid

Modify Date: 2025-08-26 13:18:56

9,10-dihydroxystearic acid Structure
9,10-dihydroxystearic acid structure
Common Name 9,10-dihydroxystearic acid
CAS Number 120-87-6 Molecular Weight 316.476
Density 1.0±0.1 g/cm3 Boiling Point 481.6±25.0 °C at 760 mmHg
Molecular Formula C18H36O4 Melting Point 92-94ºC
MSDS N/A Flash Point 259.2±19.7 °C

 Use of 9,10-dihydroxystearic acid


9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice[1].

 Names

Name 9,10-dihydroxystearic acid
Synonym More Synonyms

 9,10-dihydroxystearic acid Biological Activity

Description 9,10-Dihydroxystearic acid is an oxidation product of oleic acid. 9,10-Dihydroxystearic acid can improve glucose tolerance and insulin sensitivity in KKAy mice[1].
Related Catalog
In Vitro 5-20 μmol/L 9,10-Dihydroxystearic acid (DHSA) does not activate PPAR-γ in CV-1 cells but 50-100 μmol/L DHSA activates PPAR-γ in a dose-dependent way. 9,10-Dihydroxystearic acid does not activate PPAR-α in CV-1 cells[1].
In Vivo 9,10-Dihydroxystearic acid (DHSA; fed with high fat diet containing 4% DHSA; for 5-6 weeks) treatment improves glucose tolerance and insulin sensitivity in KKAy mice[1].
References

[1]. Xiaoming Yu, et al. Effects of 9,10-dihydroxysteatic acid on glucose metabolism in KKAy mice. Wei Sheng Yan Jiu. 2010 Jul;39(4):423-5.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 481.6±25.0 °C at 760 mmHg
Melting Point 92-94ºC
Molecular Formula C18H36O4
Molecular Weight 316.476
Flash Point 259.2±19.7 °C
Exact Mass 316.261353
PSA 77.76000
LogP 4.34
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.481
InChIKey VACHUYIREGFMSP-UHFFFAOYSA-N
SMILES CCCCCCCCC(O)C(O)CCCCCCCC(=O)O

 Safety Information

Hazard Codes Xn
HS Code 2918199090

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

9 10-DIHYDROXYOCTADECANOIC ACID
Octadecanoic acid, 9,10-dihydroxy-
9,10-DIHYDROXYSTEARIC ACID
9,10-Dihydroxyoctadecanoic acid
9,10-Dihydroxystearate
EINECS 204-432-2
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