5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

Modify Date: 2025-08-25 16:30:30

5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) structure	Common Name	5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
	CAS Number	1197033-19-4	Molecular Weight	899.96900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₉H₅₄N₇O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion[1].

Name	N-[9-[(1R,3S,4S,6R,7S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methyl-2,5-dioxabicyclo[2.2.1]heptan-6-yl]purin-6-yl]benzamide

Description	5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue. 5'-ODMT cEt N-Bz A Phosphoramidite Amidite possesses hybridization and mismatch discrimination attributes similar to those of LNA and shows resistance to exonuclease digestion[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81.

Molecular Formula	C₄₉H₅₄N₇O₈P
Molecular Weight	899.96900
Exact Mass	899.37700
PSA	181.42000
LogP	9.20458
InChIKey	XHEVZGBLRSIPCO-DZGFXGBPSA-N
SMILES	COc1ccc(C(OCC23OC(n4cnc5c(NC(=O)c6ccccc6)ncnc54)C(OC2C)C3OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

N-(9-((1R,3R,4R...

CAS#:1197033-18-3

2-Cyanoethyltet...

CAS#:102691-36-1

~95%

5'-ODMT cEt N-B...

CAS#:1197033-19-4

Literature: Seth, Punit P.; Vasquez, Guillermo; Allerson, Charles A.; Berdeja, Andres; Gaus, Hans; Kinberger, Garth A.; Prakash, Thazha P.; Migawa, Michael T.; Bhat, Balkrishen; Swayze, Eric E. Journal of Organic Chemistry, 2010 , vol. 75, # 5 p. 1569 - 1581

Precursor 1
CAS#:102691-36-1 2-Cyanoethyltet...
DownStream 0

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5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

Use of 5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.