2-bromo-5-(trifluoromethyl)pyrazine

Modify Date: 2025-08-24 19:18:50

2-bromo-5-(trifluoromethyl)pyrazine Structure
2-bromo-5-(trifluoromethyl)pyrazine structure
Common Name 2-bromo-5-(trifluoromethyl)pyrazine
CAS Number 1196152-38-1 Molecular Weight 226.98200
Density N/A Boiling Point 189.4±35.0°C at 760 mmHg
Molecular Formula C5H2BrF3N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 2-bromo-5-(trifluoromethyl)pyrazine
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 189.4±35.0°C at 760 mmHg
Molecular Formula C5H2BrF3N2
Molecular Weight 226.98200
Exact Mass 225.93500
PSA 25.78000
LogP 2.25790

 Synthetic Route

~%

2-bromo-5-(trifluoromethyl)pyrazine Structure

2-bromo-5-(trif...

CAS#:1196152-38-1

Literature: GLAXO GROUP LIMITED; AMANTINI, David; DI FABIO, Romano Patent: WO2010/122151 A1, 2010 ; Location in patent: Page/Page column 61-62 ; WO 2010/122151 A1

~59%

2-bromo-5-(trifluoromethyl)pyrazine Structure

2-bromo-5-(trif...

CAS#:1196152-38-1

Literature: Pinard, Emmanuel; Alanine, Alexander; Alberati, Daniela; Bender, Markus; Borroni, Edilio; Bourdeaux, Patrick; Brom, Virginie; Burner, Serge; Fischer, Holger; Hainzl, Dominik; Halm, Remy; Hauser, Nicole; Jolidon, Synese; Lengyel, Judith; Marty, Hans-Peter; Meyer, Thierry; Moreau, Jean-Luc; Mory, Roland; Narquizian, Robert; Nettekoven, Mathias; Norcross, Roger D.; Puellmann, Bernd; Schmid, Philipp; Schmitt, Sebastien; Stalder, Henri; Wermuth, Roger; Wettstein, Joseph G.; Zimmerli, Daniel Journal of Medicinal Chemistry, 2010 , vol. 53, # 12 p. 4603 - 4614

 Synonyms

2-bromo-5-trifluoromethyl-pyrazine
5-Bromo-2-trifluoromethylpyrazine
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