Burixafor hydrobromide (TG-0054 hydrobromide)

Modify Date: 2025-08-26 18:58:54

Burixafor hydrobromide (TG-0054 hydrobromide) structure	Common Name	Burixafor hydrobromide (TG-0054 hydrobromide)
	CAS Number	1191450-19-7	Molecular Weight	769.01
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₅₁N₈O₃P_.xHBr	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Burixafor hydrobromide (TG-0054 hydrobromide)

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].

Name	Burixafor hydrobromide

Description	Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent antagonist of CXCR4 and a well water soluble anti-angiogenic drug that is of potential value in treating choroid neovascularization[1]. Burixafor hydrobromide (TG-0054 hydrobromide) mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction[2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> CXCR Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR4
References	[1]. Shelke NB, et al. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res. 2011 Feb;1(1):76-90. [2]. Hsu WT, et al. CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction. Cell Transplant. 2015;24(7):1313-28.

Molecular Formula	C₂₇H₅₁N₈O₃P_.xHBr
Molecular Weight	769.01
InChIKey	ZXUVXYNBMUFEMK-UHFFFAOYSA-N
SMILES	Br.Nc1cc(N2CCN(CCP(=O)(O)O)CC2)nc(NCC2CCC(CNCCCNC3CCCCC3)CC2)n1
Storage condition	2-8℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Burixafor hydrobromide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Burixafor hydrobromide (TG-0054 hydrobromide)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Burixafor hydrobromide (TG-0054 hydrobromide)
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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