Chlorothiazide-13C,15N2

Modify Date: 2024-01-09 10:13:00

Chlorothiazide-13C,15N2 Structure
Chlorothiazide-13C,15N2 structure
Common Name Chlorothiazide-13C,15N2
CAS Number 1189440-79-6 Molecular Weight 298.70300
Density N/A Boiling Point N/A
Molecular Formula C7H6ClN3O4S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Chlorothiazide-13C,15N2


Chlorothiazide-13C,15N2 is the 13C and 15N labeled Chlorothiazide[1]. Chlorothiazide is an orally active diuretic and anti-hypertensive agent[2].

 Names

Name 6-chloro-1,1-dioxo-4H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Synonym More Synonyms

 Chlorothiazide-13C,15N2 Biological Activity

Description Chlorothiazide-13C,15N2 is the 13C and 15N labeled Chlorothiazide[1]. Chlorothiazide is an orally active diuretic and anti-hypertensive agent[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Babu V R, et al. Preparation and in-vitro release of chlorothiazide novel pH-sensitive chitosan-N, N′-dimethylacrylamide semi-interpenetrating network microspheres. Carbohydrate Polymers, 2008, 71(2): 208-217.

 Chemical & Physical Properties

Molecular Formula C7H6ClN3O4S2
Molecular Weight 298.70300
Exact Mass 297.94600
PSA 135.45000
LogP 2.56540

 Synonyms

6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide-13C,15N2 1,1-dioxide
Chlorothiazide-13C,15N2
Diuril-13C,15N2
6-Chloro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide-13C,15N2
Chlotride-13C,15N2
Chlorthiazide-13C,15N2
Saluric-13C,15N2