bradykinin, Phe(8)-psi-CH2NH-Arg(9)-

Modify Date: 2025-08-25 18:27:27

bradykinin, Phe(8)-psi-CH2NH-Arg(9)- Structure
bradykinin, Phe(8)-psi-CH2NH-Arg(9)- structure
Common Name bradykinin, Phe(8)-psi-CH2NH-Arg(9)-
CAS Number 118122-39-7 Molecular Weight 1046.23
Density 1.46g/cm3 Boiling Point N/A
Molecular Formula C50H75N15O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of bradykinin, Phe(8)-psi-CH2NH-Arg(9)-


[Phe8Ψ(CH-NH)Arg9]-Bradykinin is a selective Bradykinin receptor B2 agonist (not cleaved by protein kinase I/II). [Phe8Ψ(CH-NH)Arg9]-Bradykinin has potential for the research of hypertension[1].

 Names

Name (2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3
Synonym More Synonyms

 bradykinin, Phe(8)-psi-CH2NH-Arg(9)- Biological Activity

Description [Phe8Ψ(CH-NH)Arg9]-Bradykinin is a selective Bradykinin receptor B2 agonist (not cleaved by protein kinase I/II). [Phe8Ψ(CH-NH)Arg9]-Bradykinin has potential for the research of hypertension[1].
Related Catalog
Target

Bradykinin receptor B2[1].

References

[1]. Drapeau G, et al. [Phe8 psi(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Eur J Pharmacol. 1988 Oct 11;155(1-2):193-5.  

 Chemical & Physical Properties

Density 1.46g/cm3
Molecular Formula C50H75N15O10
Molecular Weight 1046.23
Exact Mass 1045.58000
PSA 410.67000
LogP 3.55230
Index of Refraction 1.686
InChIKey XKJBISGEHGXKBF-TZPCGENMSA-N
SMILES NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)NC(CNC(CCCN=C(N)N)C(=O)O)Cc1ccccc1

 Synonyms

Ppcna-BK
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