(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt

Modify Date: 2025-08-20 12:08:34

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt structure	Common Name	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt
	CAS Number	118102-98-0	Molecular Weight	3625.2
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆₅H₂₅₁N₄₉O₄₀S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation[1][2].

Name	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)

Description	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroid hormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation[1][2].
Related Catalog	Signaling Pathways >> Others >> Thyroid Hormone Receptor Research Areas >> Metabolic Disease
Target	Ki: 69 nM (PTH)[1]
In Vitro	(D-Trp12,Tyr34)-pTH (7-34) amide (0.05-10 μM) causes a concentration-dependent inhibition of PTHrP or PTH-stimulated cAMP formation in opossum kidney (OK) cells[2]. (D-Trp12,Tyr34)-pTH (7-34) amide (0.1-10 μM) attenuates inhibition of NapiT promoted by 1 nM of either PTHrP or PTH[2].
In Vivo	(D-Trp12,Tyr34)-pTH (7-34) amide (1 mg/mL once, 0.1 mg/mL for 6 h; i.v.) has no significant effect on serum calcium levels in hypercalcemic athymic nude mice bearing a human squamous cell carcinoma of the lung[3].
References	[1]. Goldma ME, et, al. A new highly potent parathyroid hormone antagonist: [D-Trp12,Tyr34]bPTH-(7-34)NH2. Endocrinology. 1988 Nov; 123(5): 2597-9. [2]. Pizurki L, et, al. Inhibition by (D-Trp12,Tyr34)bPTH(7-34)amide of PTH and PTHrP effects on Pi transport in renal cells. Am J Physiol. 1990 Aug; 259(2 Pt 2): F389-92. [3]. Kukreja SC, Inactivation by plasma may be responsible for lack of efficacy of parathyroid hormone antagonists in hypercalcemia of malignancy. Endocrinology. 1994 May; 134(5): 2184-8.

Molecular Formula	C₁₆₅H₂₅₁N₄₉O₄₀S₂
Molecular Weight	3625.2

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: (D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (D-TRP12,TYR34)-PTH (7-34) AMIDE (BOVINE)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Get all suppliers and price by the below link:

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt suppliers

Price: ￥2000/1 mg

Reference only. check more (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt price

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt

Use of (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt

Names

Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.