(2S)-ISOPROPYLPIPERAZINE

Modify Date: 2024-01-08 08:40:31

(2S)-ISOPROPYLPIPERAZINE Structure
(2S)-ISOPROPYLPIPERAZINE structure
Common Name (2S)-ISOPROPYLPIPERAZINE
CAS Number 117857-93-9 Molecular Weight 159.14000
Density N/A Boiling Point N/A
Molecular Formula C6H9NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2S)-ISOPROPYLPIPERAZINE


L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1].

 Names

Name (2S,1′S,2′S)-2-(Carboxycyclopropyl)glycine
Synonym More Synonyms

 (2S)-ISOPROPYLPIPERAZINE Biological Activity

Description L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1].
Related Catalog
Target

mGluR2:0.3 nM (EC50)

In Vitro L-CCG-I 对 mGluR2 具有活性,EC50 值为 0.3 nM[1]。 L-CCG-I 有效刺激表达 mGluR1 的细胞中的磷脂酰肌醇水解[1]。 L-CCG-I 可抑制毛喉素刺激的腺苷 3':5'-环磷酸(环AMP)在 mGluR2 表达细胞中的积累[1]。 L-CCG-I 引起 mGluR4 毛喉素刺激的环 AMP 生成特征的抑制[1]。
References

[1]. Y Hayashi, et al. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br J Pharmacol. 1992 Oct;107(2):539-43.  

 Chemical & Physical Properties

Molecular Formula C6H9NO4
Molecular Weight 159.14000
Exact Mass 159.05300
PSA 100.62000

 Safety Information

WGK Germany 3

 Synonyms

(2s,1's,2's)-2-(carboxycyclopropyl)glycine
MFCD00216830