Levofloxacin N-oxide

Modify Date: 2024-01-02 19:51:31

Levofloxacin N-oxide Structure
Levofloxacin N-oxide structure
Common Name Levofloxacin N-oxide
CAS Number 117678-38-3 Molecular Weight 377.367
Density N/A Boiling Point N/A
Molecular Formula C18H20FN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Levofloxacin N-oxide


Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2].

 Names

Name Levofloxacin N-oxide
Synonym More Synonyms

 Levofloxacin N-oxide Biological Activity

Description Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria[1][2].
Related Catalog
References

[1]. Zhu Q, et al. In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin. Toxicol Mech Methods. 2012 Apr;22(3):225-30.

[2]. Nightingale CH, et al. Pharmacodynamics and pharmacokinetics of levofloxacin. Chemotherapy. 2000;46 Suppl 1:6-14.

 Chemical & Physical Properties

Molecular Formula C18H20FN3O5
Molecular Weight 377.367
Exact Mass 377.138702
PSA 101.20000
LogP -1.03

 Synonyms

unii-ue0e2o42uc
(3S)-9-Fluoro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-4-oxido-1-piperazinyl)-7-oxo-, (3S)-
Levofloxacin Impurity 1