LY223982
Modify Date: 2025-08-25 19:04:05
LY223982 structure
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Common Name | LY223982 | ||
|---|---|---|---|---|
| CAS Number | 117423-74-2 | Molecular Weight | 502.555 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 753.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C30H30O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 248.4±26.4 °C | |
Use of LY223982LY223982 is a potent and specific inhibitor of leukotriene B4 receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. |
| Name | [3h]-skf 107324 |
|---|---|
| Synonym | More Synonyms |
| Description | LY223982 is a potent and specific inhibitor of leukotriene B4 receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. |
|---|---|
| Related Catalog | |
| Target |
LTB4:13.2 nM (IC50) |
| In Vitro | LY223982 is a potent and specific inhibitor of leukotriene B4 (LTB4) receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. LY223982 is also a potent antagonist of the aggregation of human neutrophils by LTB4 (IC50, 100 nM)[1]. |
| In Vivo | LY223982 inhibits transient leukopenia induced in rabbits with LTB4 (ED50, 3 mg/kg) but not with FMLP, and shows no agonist activity in any of the test systems[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 753.8±60.0 °C at 760 mmHg |
| Molecular Formula | C30H30O7 |
| Molecular Weight | 502.555 |
| Flash Point | 248.4±26.4 °C |
| Exact Mass | 502.199158 |
| PSA | 110.13000 |
| LogP | 6.32 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.612 |
| Storage condition | 2-8℃ |
| Gonyaulax toxin |
| 3-[3-(2-Carboxyethyl)-4-{[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy}benzoyl]benzoic acid |
| mytiluscalifornianuspoison |
| saxidomusgiganteuspoison |
| SAXITOXIN DIACETATE SALT |
| Benzenepropanoic acid, 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexen-1-yl]oxy]- |
| gonyaulaxcatenellapoison |
| Mussel poison |