Gemcitabine Monophosphate Formate Salt

Modify Date: 2024-01-08 14:32:22

Gemcitabine Monophosphate Formate Salt structure	Common Name	Gemcitabine Monophosphate Formate Salt
	CAS Number	116371-67-6	Molecular Weight	343.17800
	Density	2.09	Boiling Point	618.3ºC at 760 mmHg
	Molecular Formula	C₉H₁₂F₂N₃O₇P	Melting Point	151-153 °C
	MSDS	N/A	Flash Point	327.736ºC

Use of Gemcitabine Monophosphate Formate Salt

Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate shows synergistic anti-cancer effects[1][2].

Name	[(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate,formic acid
Synonym	More Synonyms

Description	Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate shows synergistic anti-cancer effects[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhang Y, et al. Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC. Mol Ther. 2013 Aug;21(8):1559-69. [2]. Miao L, et al. Nanoparticles with Precise Ratiometric Co-Loading and Co-Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer. Adv Funct Mater. 2014 Nov 12;24(42):6601-6611.

Description

Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate shows synergistic anti-cancer effects[1][2].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

References

[1]. Zhang Y, et al. Codelivery of VEGF siRNA and gemcitabine monophosphate in a single nanoparticle formulation for effective treatment of NSCLC. Mol Ther. 2013 Aug;21(8):1559-69.

[2]. Miao L, et al. Nanoparticles with Precise Ratiometric Co-Loading and Co-Delivery of Gemcitabine Monophosphate and Cisplatin for Treatment of Bladder Cancer. Adv Funct Mater. 2014 Nov 12;24(42):6601-6611.

Density	2.09
Boiling Point	618.3ºC at 760 mmHg
Melting Point	151-153 °C
Molecular Formula	C₉H₁₂F₂N₃O₇P
Molecular Weight	343.17800
Flash Point	327.736ºC
Exact Mass	343.03800
PSA	166.94000
Index of Refraction	1.681