Tecovirimat hydrate
Tecovirimat hydrate structure
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Common Name | Tecovirimat hydrate | ||
|---|---|---|---|---|
| CAS Number | 1162664-19-8 | Molecular Weight | 394.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H17F3N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tecovirimat hydrateTecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to prevent disease by blocking the cellular transmission of the virus. |
| Name | Tecovirimat hydrate |
|---|
| Description | Tecovirimat,(ST-246, SIgA-246) is an inhibitor of p37 envelope proteins used to treat smallpox infection. Tecovirimat is an antiviral drug that is active against orthopoxviruses such as smallpox and is currently undergoing clinical trials. Its role is to prevent disease by blocking the cellular transmission of the virus. |
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| References | 1. Berhanu A, Prigge JT, Silvera PM, Honeychurch KM, Hruby DE, Grosenbach DW. Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection. Antimicrob Agents Chemother. 2015 Jul;59(7):4296-300. doi: 10.1128/AAC.00208-15. Epub 2015 Apr 20. PubMed PMID: 25896687; PubMed Central PMCID: PMC4468657. |
| Molecular Formula | C19H17F3N2O4 |
|---|---|
| Molecular Weight | 394.35 |
| InChIKey | QRHXYGPOQKLBJP-NPIFKJBVSA-N |
| SMILES | O.O=C(NN1C(=O)C2C3C=CC(C4CC34)C2C1=O)c1ccc(C(F)(F)F)cc1 |