Ibuprofen Acyl-b-D-glucuronide
Modify Date: 2024-01-06 15:26:21
Ibuprofen Acyl-b-D-glucuronide structure
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Common Name | Ibuprofen Acyl-b-D-glucuronide | ||
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| CAS Number | 115075-59-7 | Molecular Weight | 382.40500 | |
| Density | 1.34g/cm3 | Boiling Point | 567.3ºC at 760 mmHg | |
| Molecular Formula | C19H26O8 | Melting Point | 26-28ºC | |
| MSDS | USA | Flash Point | 198.3ºC | |
| Name | Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) |
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| Synonym | More Synonyms |
| Density | 1.34g/cm3 |
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| Boiling Point | 567.3ºC at 760 mmHg |
| Melting Point | 26-28ºC |
| Molecular Formula | C19H26O8 |
| Molecular Weight | 382.40500 |
| Flash Point | 198.3ºC |
| Exact Mass | 382.16300 |
| PSA | 133.52000 |
| LogP | 0.42400 |
| Vapour Pressure | 1.05E-13mmHg at 25°C |
| Index of Refraction | 1.581 |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Stability | Hygroscopic, Not stable in aqueous solutions. |
| RIDADR | NONH for all modes of transport |
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Direct determination of ibuprofen and ibuprofen acyl glucuronide in plasma by high-performance liquid chromatography using solid-phase extraction.
J. Chromatogr. A. 614(1) , 109-16, (1993) A method for the simultaneous determination of ibuprofen and its labile, reactive metabolite, ibuprofen acyl glucuronide, in plasma is described. Reversed-phase high-performance liquid chromatography ... |
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Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
Drug Metab. Dispos. 23(5) , 566-72, (1995) The disposition of ibuprofen and ibufenac, an analog of ibuprofen with a history of severe adverse reactions, was investigated in Rhesus monkeys after oral administration. Plasma concentrations of the... |
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Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4.
J. Pharmacol. Exp. Ther. 356 , 366-74, (2016) Combined administration of methotrexate (MTX) and nonsteroidal anti-inflammatory drugs (NSAIDs) can result in a decreased systemic clearance of MTX. To date, inhibition of renal uptake via organic ani... |
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