Golgicide A
Modify Date: 2025-09-17 18:17:53
Golgicide A structure
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Common Name | Golgicide A | ||
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| CAS Number | 1139889-93-2 | Molecular Weight | 284.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H14F2N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Golgicide AGolgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1]. |
| Name | (3aR,9bS)-6,8-Difluoro-4-(3-pyridinyl)-3a,4,5,9b-tetrahydro-3H-cy clopenta[c]quinoline |
|---|---|
| Synonym | More Synonyms |
| Description | Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF), GBF1[1]. |
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| Related Catalog | |
| Target |
GBF1[1] |
| In Vitro | Golgicide A (GCA) is a potent and highly effective inhibitor of shiga toxin activity. Golgicide A (GCA) inhibits the effect of shiga toxin on protein synthesis with an IC50 of 3.3 μM[1]. |
| References |
| Molecular Formula | C17H14F2N2 |
|---|---|
| Molecular Weight | 284.30 |
| Exact Mass | 284.11300 |
| PSA | 24.92000 |
| LogP | 4.32430 |
| InChIKey | NJZHEQOUHLZCOX-FTLRAWMYSA-N |
| SMILES | Fc1cc(F)c2c(c1)C1C=CCC1C(c1cccnc1)N2 |
| Storage condition | Store at RT |
| Golgicide A |