Ilexhainanoside D

Modify Date: 2025-08-25 20:21:35

Ilexhainanoside D Structure
Ilexhainanoside D structure
Common Name Ilexhainanoside D
CAS Number 1137648-52-2 Molecular Weight 664.83
Density 1.35±0.1 g/cm3(Predicted) Boiling Point 788.1±60.0 °C(Predicted)
Molecular Formula C36H56O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ilexhainanoside D


Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1].

 Names

Name Ilexhainanoside D

 Ilexhainanoside D Biological Activity

Description Ilexhainanoside D is the main triterpenoid saponin extracted from Ilex hainanensis Merr., and the combination of Ilexhainanoside D and ilexsaponin A1 has anti-inflammation effect[1].
Related Catalog
In Vivo The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240 mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines[1].
References

[1]. Zhao W, et al. The combination of Ilexhainanoside D and ilexsaponin A1 reduces liver inflammation and improves intestinal barrier function in mice with high-fat diet-induced non-alcoholic fatty liver disease. Phytomedicine. 2019 Jul 26;63:153039.

 Chemical & Physical Properties

Density 1.35±0.1 g/cm3(Predicted)
Boiling Point 788.1±60.0 °C(Predicted)
Molecular Formula C36H56O11
Molecular Weight 664.83
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