Rivaroxaban D4

Modify Date: 2024-01-04 18:14:44

Rivaroxaban D4 structure	Common Name	Rivaroxaban D4
	CAS Number	1132681-38-9	Molecular Weight	439.90600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₄D₄ClN₃O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Rivaroxaban D4

Rivaroxaban D4 (BAY 59-7939 D4) is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent，selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].

Name	5-chloro-N-[[(5S)-2-oxo-3-[2,3,5,6-tetradeuterio-4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
Synonym	More Synonyms

Description	Rivaroxaban D4 (BAY 59-7939 D4) is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent，selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Factor Xa
Target	IC50: 0.7 nM (Factor Xa); Ki: 0.4 nM (Factor Xa)[1][2]
References	[1]. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19) [2]. Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21.

Molecular Formula	C₁₉H₁₄D₄ClN₃O₅S
Molecular Weight	439.90600
Exact Mass	439.09100
PSA	116.42000
LogP	3.04080
InChIKey	KGFYHTZWPPHNLQ-UJCPGTITSA-N
SMILES	O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1ccc(Cl)s1
Storage condition	2-8°C

BAY 59-7939-d4

5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

Rivaroxaban-d4

[2H4]-Rivaroxaban

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Rivaroxaban D4

Use of Rivaroxaban D4

Names

Rivaroxaban D4 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.