Gramicidin S

Modify Date: 2025-08-25 18:26:22

Gramicidin S Structure
Gramicidin S structure
Common Name Gramicidin S
CAS Number 113-73-5 Molecular Weight 1141.447
Density 1.2±0.1 g/cm3 Boiling Point 1394.8±65.0 °C at 760 mmHg
Molecular Formula C60H92N12O10 Melting Point N/A
MSDS N/A Flash Point 797.4±34.3 °C

 Use of Gramicidin S


Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1].

 Names

Name gramicidin S
Synonym More Synonyms

 Gramicidin S Biological Activity

Description Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1].
Related Catalog
References

[1]. Mogi T, et al. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci. 2009 Dec;66(23):3821-6.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 1394.8±65.0 °C at 760 mmHg
Molecular Formula C60H92N12O10
Molecular Weight 1141.447
Flash Point 797.4±34.3 °C
Exact Mass 1140.705933
PSA 353.38000
LogP 0.10
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.596
InChIKey IUAYMJGZBVDSGL-XNNAEKOYSA-N
SMILES CC(C)CC1NC(=O)C(CCCN)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(Cc2ccccc2)NC(=O)C(CC(C)C)NC(=O)C(CCCN)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(Cc2ccccc2)NC1=O

 Synonyms

5H,22H-dipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-5,22-dione, 12,29-bis(3-aminopropyl)-1,2,3,6,9,12,15,17a,18,19,20,23,26,29,32,34a-hexadecahydro-8,11,14,17,25,28,31,34-octahydroxy-15,32-bis(1-methylethyl)-9,26-bis(2-methylpropyl)-6,23-bis(phenylmethyl)-, (6R,7E,9S,10E,12S,13E,15S,16E,17aS,23R,24E,26S,27E,29S,30E,32S,33E,34aS)-
Gramicidin C
Cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl)
Gramacidine S [INN-French]
Gramicin S 1
Gramicidinum S [INN-Latin]
Gramicidina S [INN-Spanish]
gramicidin s
Gramicin S-A
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