UCN-01
UCN-01 structure
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Common Name | UCN-01 | ||
|---|---|---|---|---|
| CAS Number | 112953-11-4 | Molecular Weight | 482.53000 | |
| Density | 1.63g/cm3 | Boiling Point | 705.7ºC at 760mmHg | |
| Molecular Formula | C28H26N4O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 380.6ºC | |
Use of UCN-01UCN-01 (7-Hydroxystaurosporine. |
| Name | 7-Hydroxystaurosporine |
|---|---|
| Synonym | More Synonyms |
| Density | 1.63g/cm3 |
|---|---|
| Boiling Point | 705.7ºC at 760mmHg |
| Molecular Formula | C28H26N4O4 |
| Molecular Weight | 482.53000 |
| Flash Point | 380.6ºC |
| Exact Mass | 482.19500 |
| PSA | 89.68000 |
| LogP | 4.56460 |
| Vapour Pressure | 6.64E-21mmHg at 25°C |
| Index of Refraction | 1.827 |
| Storage condition | -20°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| RIDADR | NONH for all modes of transport |
|---|---|
| RTECS | KC6600010 |
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Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation.
BMC Cancer 15 , 17, (2015) DNAX accessory molecule-1 (DNAM-1) is an activating receptor constitutively expressed by macrophages/dendritic cells and by T lymphocytes and Natural Killer (NK) cells, having an important role in ant... |
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Induction of DNA damage and G2 cell cycle arrest by diepoxybutane through the activation of the Chk1-dependent pathway in mouse germ cells.
Chem. Res. Toxicol. 28(3) , 518-31, (2015) 1,2:3,4-Diepoxybutane (DEB) is a major carcinogenic metabolite of 1,3-butadiene (BD), which has been shown to cause DNA strand breaks in cells through its potential genotoxicity. The adverse effect of... |
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The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux.
Autophagy 11 , 1373-88, (2015) Oncogenic mutation of KRAS (Kirsten rat sarcoma viral oncogene homolog) in colorectal cancer (CRC) confers resistance to both chemotherapy and EGFR (epidermal growth factor receptor)-targeted therapy.... |
| UCN-01 |
| 1okz |