IAXO-102

Modify Date: 2024-01-17 22:53:51

IAXO-102 Structure
IAXO-102 structure
Common Name IAXO-102
CAS Number 1115270-63-7 Molecular Weight 585.94
Density N/A Boiling Point N/A
Molecular Formula C35H71NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IAXO-102


IAXO-102 is a TLR4 antagonist, inhibits MAPK and p65 NF-kB phosphorylation involved in down regulation of the expression of TLR4 and TLR4 dependent proinflammatory protein. IAXO-102 prevents experimental abdominal aortic aneurysm development[1].

 Names

Name IAXO-102

 IAXO-102 Biological Activity

Description IAXO-102 is a TLR4 antagonist, inhibits MAPK and p65 NF-kB phosphorylation involved in down regulation of the expression of TLR4 and TLR4 dependent proinflammatory protein. IAXO-102 prevents experimental abdominal aortic aneurysm development[1].
Related Catalog
Target

TLR4

References

[1]. Huggins C, et al. A novel small molecule TLR4 antagonist (IAXO-102) negatively regulates non-hematopoietic toll like receptor 4 signalling and inhibits aortic aneurysms development. Atherosclerosis. 2015 Oct;242(2):563-70.

 Chemical & Physical Properties

Molecular Formula C35H71NO5
Molecular Weight 585.94