(-)-taxifolin

Modify Date: 2025-08-25 14:31:09

(-)-taxifolin structure	Common Name	(-)-taxifolin
	CAS Number	111003-33-9	Molecular Weight	304.252
	Density	1.7±0.1 g/cm3	Boiling Point	687.6±55.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₁₂O₇	Melting Point	232-234 ºC (ethanol )
	MSDS	N/A	Flash Point	264.2±25.0 °C

Use of (-)-taxifolin

(-)-Taxifolin is the less active enantiomer of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].

Name	(-)-taxifolin
Synonym	More Synonyms

Description	(-)-Taxifolin is the less active enantiomer of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21(11):1586. [2]. Lei Ren, et al. Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy. Front Pharmacol. 2021 Jan 14;11:608511.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Angelis A, et al. Bio-Guided Isolation of Methanol-Soluble Metabolites of Common Spruce (Picea abies) Bark by-Products and Investigation of Their Dermo-Cosmetic Properties. Molecules. 2016 Nov 21;21(11):1586.

[2]. Lei Ren, et al. Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy. Front Pharmacol. 2021 Jan 14;11:608511.

Density	1.7±0.1 g/cm3
Boiling Point	687.6±55.0 °C at 760 mmHg
Melting Point	232-234 ºC (ethanol )
Molecular Formula	C₁₅H₁₂O₇
Molecular Weight	304.252
Flash Point	264.2±25.0 °C
Exact Mass	304.058289
LogP	1.82
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.763
Water Solubility	Very slightly soluble (0.97 g/L) (25 ºC)