EM574

Modify Date: 2024-01-10 17:29:26

EM574 Structure
EM574 structure
Common Name EM574
CAS Number 110480-13-2 Molecular Weight 743.96
Density 1.18g/cm3 Boiling Point 804ºC at 760mmHg
Molecular Formula C39H69NO12 Melting Point N/A
MSDS N/A Flash Point 440.1ºC

 Use of EM574


EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative[1].

 Names

Name Ddz-L-phenylalanine
Synonym More Synonyms

 EM574 Biological Activity

Description EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative[1].
Related Catalog
References

[1]. Guanfa Gan, et al. Intestinal absorption and presystemic elimination of the prokinetic agent, EM574, in the rabbit. J Pharm Sci. 2002 Jan;91(1):217-28.

 Chemical & Physical Properties

Density 1.18g/cm3
Boiling Point 804ºC at 760mmHg
Molecular Formula C39H69NO12
Molecular Weight 743.96
Flash Point 440.1ºC
Exact Mass 743.48200
PSA 165.84000
LogP 3.67090
Vapour Pressure 6.53E-30mmHg at 25°C
Index of Refraction 1.538

 Synonyms

Ddz-Phe-OH
(2S)-2-[({[2-(3,5-dimethoxyphenyl)propan-2-yl]oxy}carbonyl)amino]-3-phenylpropanoic acid
Ddz-L-Phe-OH
de(N-methyl)-N-isopropyl-8,9-anhydroerythromycin A 6,9-hemiacetal