N-Methylparoxetine

Modify Date: 2024-01-02 16:24:20

N-Methylparoxetine Structure
N-Methylparoxetine structure
Common Name N-Methylparoxetine
CAS Number 110429-36-2 Molecular Weight 343.392
Density 1.2±0.1 g/cm3 Boiling Point 443.7±45.0 °C at 760 mmHg
Molecular Formula C20H22FNO3 Melting Point 111 °C
MSDS N/A Flash Point 222.1±28.7 °C
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Use of N-Methylparoxetine


N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes. It inhibits serotonin (5-HT) uptake in rat brain synaptosomes and has been used as a precursor in the synthesis of paroxetine.

 Names

Name N-Methyl Paroxetine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 443.7±45.0 °C at 760 mmHg
Melting Point 111 °C
Molecular Formula C20H22FNO3
Molecular Weight 343.392
Flash Point 222.1±28.7 °C
Exact Mass 343.158386
PSA 30.93000
LogP 3.91
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.562
Storage condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H410
Precautionary Statements P273-P301 + P310-P501
Hazard Codes T,N
Risk Phrases 25-50/53
Safety Phrases 45-60-61
RIDADR UN 2811 6.1 / PGIII
Hazard Class 6.1

 Articles1

More Articles
Depletion of selective serotonin reuptake inhibitors during sewage sludge composting.

Waste Manag. 29(11) , 2808-15, (2009)

Sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (SSRI...

 Synonyms

Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methyl-
Paroxetine Related Compound F
3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methyl-, (3S,4R)-
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)-1-methylpiperidine
MFCD03788781
N-Methyl Paroxetine
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
Paroxetine Impurity 9
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