TM-233

TM-233 Structure
TM-233 structure
Common Name TM-233
CAS Number 1103745-28-3 Molecular Weight 384.42
Density N/A Boiling Point N/A
Molecular Formula C25H20O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TM-233


TM-233 is an inhibitor of both JAK/STAT and proteasome activities that acts by inducing cell death in myeloma cells.

 Names

Name TM-233

 TM-233 Biological Activity

Description TM-233 is an inhibitor of both JAK/STAT and proteasome activities that acts by inducing cell death in myeloma cells.
References 1. Sagawa M, Tabayashi T, Kimura Y, Tomikawa T, Nemoto-Anan T, Watanabe R, Tokuhira M, Ri M, Hashimoto Y, Iida S, Kizaki M. TM-233, a novel analog of 1'-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities. Cancer Sci. 2015 Apr;106(4):438-46. doi: 10.1111/cas.12616. Epub 2015 Mar 10. PubMed PMID: 25613668; PubMed Central PMCID: PMC4409888.

 Chemical & Physical Properties

Molecular Formula C25H20O4
Molecular Weight 384.42
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