TOSAGESTIN

Modify Date: 2025-09-20 17:05:13

TOSAGESTIN Structure
TOSAGESTIN structure
Common Name TOSAGESTIN
CAS Number 110072-15-6 Molecular Weight 308.41400
Density N/A Boiling Point N/A
Molecular Formula C21H24O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TOSAGESTIN


Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].

 Names

Name (17alpha)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one
Synonym More Synonyms

 TOSAGESTIN Biological Activity

Description Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2].
Related Catalog
References

[1]. Schoonen WG, et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Mol Biol. 1995;55(3-4):439-444. 、  

[2]. Obruca A, et al. Ovarian function during and after treatment with the new progestagen Org 30659. Fertil Steril. 2001;76(1):108-115.  

 Chemical & Physical Properties

Molecular Formula C21H24O2
Molecular Weight 308.41400
Exact Mass 308.17800
PSA 37.30000
LogP 3.43460

 Synonyms

(17α)-17-hydroxy-11-methylene-19-norpregna-4,15-diene-20-yn-3-one
(8R,9S,10R,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methyl-11-methylene-1,2,6,7,8,9,10,11,12,13,14,17-dodecahydro-cyclopenta[a]phenanthren-3-one
[3H]-Tosagestin
17β-hydroxy-11-methylene-19-nor-17α-pregna-4,15-dien-20-yn-3-one
Tosagestin
11-methylene-17α-ethinyl-17β-hydroxy-oestra-4,15-dien-3-one
(17α)-17-hydroxy-11-methylene-19-norpregna-4, 15-dien-20-yn-3-one
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