Phenol-amido-C1-PEG3-N3

Modify Date: 2024-01-02 11:47:15

Phenol-amido-C1-PEG3-N3 Structure
Phenol-amido-C1-PEG3-N3 structure
Common Name Phenol-amido-C1-PEG3-N3
CAS Number 1096439-18-7 Molecular Weight 324.33
Density N/A Boiling Point N/A
Molecular Formula C14H20N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Phenol-amido-C1-PEG3-N3


PROTAC Linker 21 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 21 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 21

 Phenol-amido-C1-PEG3-N3 Biological Activity

Description PROTAC Linker 21 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 21 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C14H20N4O5
Molecular Weight 324.33
Storage condition 2-8°C
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