N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide

Modify Date: 2024-01-08 12:15:47

N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide Structure
N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide structure
Common Name N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
CAS Number 1086063-46-8 Molecular Weight 379.177
Density 1.7±0.1 g/cm3 Boiling Point 435.2±55.0 °C at 760 mmHg
Molecular Formula C12H9BrF2N2O3S Melting Point N/A
MSDS N/A Flash Point 217.0±31.5 °C

 Names

Name N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 435.2±55.0 °C at 760 mmHg
Molecular Formula C12H9BrF2N2O3S
Molecular Weight 379.177
Flash Point 217.0±31.5 °C
Exact Mass 377.948517
PSA 76.67000
LogP 4.61
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.606

 Safety Information

HS Code 2935009090

 Synthetic Route

~81%

N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide Structure

N-(5-Bromo-2-me...

CAS#:1086063-46-8

Literature: GLAXOSMITHKLINE LLC; BOTYANSZKI, Janos; DICKERSON, Scott Howard; LEIVERS, Martin Robert; LI, Xiaofei; MCFADYEN, Robert Blount; REDMAN, Aniko Maria; SHOTWELL, John Bradford; XUE, Jianjun Patent: WO2012/174312 A2, 2012 ; Location in patent: Page/Page column 214 ; WO 2012/174312 A2

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N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide Structure

N-(5-Bromo-2-me...

CAS#:1086063-46-8

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; WUNBERG, Tobias; VEEN, Van Der, Lars; KRAEMER, Oliver Patent: WO2012/101186 A1, 2012 ; WO 2012/101186 A1

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N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide Structure

N-(5-Bromo-2-me...

CAS#:1086063-46-8

Literature: GLAXOSMITHKLINE LLC; BOTYANSZKI, Janos; DICKERSON, Scott Howard; LEIVERS, Martin Robert; LI, Xiaofei; MCFADYEN, Robert Blount; REDMAN, Aniko Maria; SHOTWELL, John Bradford; XUE, Jianjun Patent: WO2012/174312 A2, 2012 ; WO 2012/174312 A2

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N-(5-Bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide Structure

N-(5-Bromo-2-me...

CAS#:1086063-46-8

Literature: Wang, Min; Gao, Mingzhang; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1569 - 1574

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

Benzenesulfonamide, N-(5-bromo-2-methoxy-3-pyridinyl)-2,4-difluoro-
N-(5-bromo-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
N-(5-Bromo-2-methoxy-3-pyridinyl)-2,4-difluorobenzenesulfonamide
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