12-OxoETE

Modify Date: 2025-09-19 19:03:27

12-OxoETE Structure
12-OxoETE structure
Common Name 12-OxoETE
CAS Number 108437-64-5 Molecular Weight 318.450
Density 1.0±0.1 g/cm3 Boiling Point 494.9±45.0 °C at 760 mmHg
Molecular Formula C20H30O3 Melting Point N/A
MSDS N/A Flash Point 267.2±25.2 °C

 Use of 12-OxoETE


12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence[1][2].

 Names

Name 12-oxo-ETE
Synonym More Synonyms

 12-OxoETE Biological Activity

Description 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via leukotriene B4 receptor or a common activation sequence[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Naccache PH, Leblanc Y, Rokach J, Patrignani P, Fruteau de Laclos B, Borgeat P. Calcium mobilization and right-angle light scatter responses to 12-oxo-derivatives of arachidonic acid in neutrophils: evidence for the involvement of the leukotriene B4 receptor. Biochim Biophys Acta. 1991 Dec 3;1133(1):102-6.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 494.9±45.0 °C at 760 mmHg
Molecular Formula C20H30O3
Molecular Weight 318.450
Flash Point 267.2±25.2 °C
Exact Mass 318.219482
PSA 54.37000
LogP 5.18
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.506
InChIKey GURBRQGDZZKITB-GVIPNGEASA-N
SMILES CCCCCC=CCC(=O)C=CC=CCC=CCCCC(=O)O
Storage condition -20°C

 Synonyms

(5Z,8Z,10E,14Z)-12-Oxo-5,8,10,14-icosatetraenoic acid
12-Oxo-ETE
12-Oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid
5,8,10,14-Eicosatetraenoic acid, 12-oxo-, (5Z,8Z,10E,14Z)-
12-oxoicosa-5,8,10,14-tetraenoic acid
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