2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE

Modify Date: 2024-01-03 18:26:19

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure
2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE structure
Common Name 2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE
CAS Number 1079-73-8 Molecular Weight 208.64400
Density 1.36g/cm3 Boiling Point N/A
Molecular Formula C10H9ClN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-(4-chlorophenyl)-4,5-dihydro-1H-pyridazin-6-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.36g/cm3
Molecular Formula C10H9ClN2O
Molecular Weight 208.64400
Exact Mass 208.04000
PSA 44.95000
LogP 1.66560
Index of Refraction 1.641

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6357000
CHEMICAL NAME :
3(2H)-Pyridazinone, 4,5-dihydro-6-(4-chlorophenyl)-
CAS REGISTRY NUMBER :
1079-73-8
BEILSTEIN REFERENCE NO. :
0163382
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H9-Cl-N2-O
MOLECULAR WEIGHT :
208.66

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 28,537,1976

 Safety Information

HS Code 2933990090

 Synthetic Route

~77%

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure

2,3,4,5-TETRAHY...

CAS#:1079-73-8

Literature: Kane; Huber; Miller; Kehne Pharmazie, 1992 , vol. 47, # 4 p. 249 - 251

~%

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure

2,3,4,5-TETRAHY...

CAS#:1079-73-8

Literature: Islam, Mojahidul; Siddiqui, Anees A. Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 555 - 562

~58%

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure

2,3,4,5-TETRAHY...

CAS#:1079-73-8

Literature: Khan; Siddiqui Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2000 , vol. 39, # 8 p. 614 - 619

~%

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure

2,3,4,5-TETRAHY...

CAS#:1079-73-8

Literature: Hashem, A. I.; Shaban, M. E.; El-Kafrawy, A. F. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, p. 763 - 764

~%

2,3,4,5-TETRAHYDRO-6(4-CHLOROPHENYL)-3(2H)-PYRIDAZINONE Structure

2,3,4,5-TETRAHY...

CAS#:1079-73-8

Literature: Mishra, Ravinesh; Siddiqui, Anees A.; Husain, Asif; Rashid, Mohd.; Goda, Chirag Journal of Enzyme Inhibition and Medicinal Chemistry, 2013 , vol. 28, # 3 p. 552 - 559

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6-(chloro)-2,3,4,5-tetrahydropyridazine-3-one
6-(4-chlorophenyl)-2,4,5-trihydropyridazin-3-one
6-(4-chlorphenyl)-4,5-dihydropyridazine-3(2H)-one
3-p-Chlorophenylpyridazin-6-one
6-(4-chloro-phenyl)-4,5-dihydro-2H-pyridazin-3-one
6-(4-chlorophenyl)-2,3,4,5-tetrahydropyridazin-3-one
3(2H)-Pyridazinone,4,5-dihydro-6-(4-chlorophenyl)
6-(p-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone
6-(4-chlorophenyl)-4,5-dihydropyridazin-3(2H)-one
6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone
6-(4-chlorophenyl)-4,5-dihydropyridazinone
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